|Twiggy in her hamster wheel|
|Nickname:||Little Rat by Princess|
|First appearance:||"Stuck Up, Up, and Away"|
|Last appearance:||"Gettin' Twiggy With It"|
|Voice actor:||Frank Welker|
Twiggy is the Pokey Oaks' kindergarten class hamster. Every Friday, a Pokey Oak's student has to take Twiggy home and care for her. She was once turned into a monster hamster in "Gettin' Twiggy With It" because Mitch Mitchelson purposely flushed her down the toilet and she got mutated by a radioactive chemical in the sewer, similar to Peepi's case in the Invader Zim episode "Hamstergeddon", where he is turned into a monster by Zim. At the end of the episode, she tries to destroy and eat Mitch as revenge for cruelly torturing her. She also dislikes Princess Morbucks, who insulted her. She kept running really fast on her hamster wheel, causing her cage to fall off the table and break.
Twiggy is a friendly hamster, especially towards the kids in Pokey Oaks, being a hamster, she likes being treated with kindness, love, and care. So she doesn't like being insulted, abuse, or torture by anyone.
When Mitch Mitchelson looks after her, he treated her with nothing more than cruelly and was deeply frightened of him. After being flushed down the toilet and fell into a radioactive wave, Twiggy developed more a vengeful personality toward Mitch and was no longer afraid of him due to being bigger than the boy, Twiggy also developed darker side in a attempt to seek revenge on Mitch which involves eating him for treating her with such unkindness.
- Stuck Up, Up, and Away
- Daylight Savings (seen sleeping in a cameo appearance)
- Gettin' Twiggy With It
- It is unknown if she ever gets turned back to a normal hamster, after Gettin' Twiggy With It.
- She is similar to Peepi from the Invader Zim episode "Hamstergeddon", as both are class pets and are turned into monsters (Peepi by Zim and her by Mitch).
- She is also similar to Cuddles the Hamster from the Goosebumps book, Monster Blood II. As both were turned into a monster.
- Blossom mistakenly thinks she's a boy.
- Her appearance is similar to Hamtaro.