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The Steamypuff Girls are the ancestors of the Powerpuff Girls, as seen in "West in Pieces", created by the ancestor of Professor Utonium to protect the town of Townsville from Mojo the Kid, who had just robbed the first bank and kicked the Sheriff, The Mayor of Townsville's ancestor, out of town. Like their descendants, their names are Blossom, Bubbles and Buttercup. The Steamypuff Girls are made of sassafras, arsenic and everything old-fashioned, with coal as the accidental extra ingredient, and they use coal-powered steam engines strapped to them to fight crime.

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