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Sister Sitter
Season 1, Episode 21
Episode name pun on: From the old ABC television show Sister, Sister and alliteration
Sister Sitter Title Card.png
Airdate: June 23, 2016
Director: Nick Jennings
Bob Boyle
Story: Jaydeep Hasrajani
Leticia Abreu Silva
Writer(s): Jake Goldman
See also
"Bubbles of the Opera"
"Odd Bubbles Out"

Sister Sitter is the twenty-first episode of the 2016 Powerpuff Girls series. It aired in United States on Cartoon Network on June 23, 2016.


Blossom and Bubbles come down with swine flu and have to skip school. When the Professor is needed at a job interview, Buttercup, seeing an opportunity to take a day off from school herself, offers to look after the two in his place. But when she neglects to do her duties properly, the girls' symptoms get worse and Buttercup has to take responsibility when their sickness turns them into giant warthogs. But can Buttercup take time to turn her sisters back to normal?


The episode begins with Blossom and Bubbles getting sickness called "Spotted Piglet Fever". Professor Utonium takes them to bed and has them skip school. He then uses the antidote by singing the song while keeping their symptoms in change. Then, Schedulebot comes in telling him that he has a job interview today. Buttercup then realizes that she has to stay home and take care of her sisters. She then tells the Professor that she is really responsible.

Then, Buttercup is in the living room sitting on the couch, along with her snacks, and watches a show called "Judge Trudy" (A parody of "Judge Judy"). Then, Buttercup is called by Blossom and Bubbles. Bubbles is freezing in the snows of Everest, and Blossom needs to be quizzed on her fractions. Schedulebot comes inside and tells Buttercup that it is time to take the girls' antidote. Buttercup then sings the song and puts the spoon on Bubbles' mouth, and the whole bottle in Blossom's mouth. Then, she flies back to the living room to watch her show, but, she missed it. Buttercup gets out her bucket list and does the things she has to do. Yelling at a bird, and make a giant straw. She uses the straws to drink sodas, but, she says it was the last straw. Then, she flies out to the store to get more straws.

While at the job interview, Professor Utomium and the Female Interviewer are arriving at Corn Co. Labs (mostly known as Cornlussus). At home, the girls are still sleeping and Schedulebot tells Buttercup that is is antidote time. He tries finding Buttercup, but she is not here. Then, Blossom and Bubbles are still sleeping as they transform into warthogs. Schedulebot goes to the girls' bedroom and see that they have turned into warthogs.

At the store, Buttercup picks one of her straws that she can use. Schedulebot comes inside and tells her it is antidote time. Buttercup sees that Blossom and Bubbles are turned into warthogs. Schedulebot says that the side effects of the sickness is to turn into warthogs without taking the antidote. Buttercup says that it is time to get serious and she backflips out of the crashed window.

At the Food Truck parade, Blossom and Bubbles wreck havoc by eating the trucks. Buttercup barges in, telling her sisters to stop turning into warthogs. At the job interview, Professor Utonium and the Female Interviewer are telling about the girls how responsible they are. Then, Buttercup tries to give the antidote to Blossom and Bubbles, but she is crashed by Blossom. She pounces on Schedulebot and tells him how to make her sisters drink the antidote. Then, Schedulebot tells her to sing the song. Then, Buttercup powers up into an airplane to make her sisters take the antidote. She starts singing the song and fires 2 antidote spoons to Blossom and Bubbles. The sisters start to turn back to normal as Buttercup takes them home.

Professor Utonium comes home with his job interview and sees Buttercup taking care of her sisters. Buttercup tells him that she will be watching a Judge Trudy marathon. She then gets Spotted Piglet Fever, too as Professor Utonium takes her to the couch to feel better.

The episode ends with Schedulebot, who is crashed by Buttercup, and says "Antidote time".


Main Characters

Minor Characters



  • Judge Trudy is a parody of the reality courtroom television show Judge Judy.
    • Coincidentally, Judge Trudy shares its name and premise with a regular sketch on The Amanda Show.
  • This episode plot is barely and slightly similar from the Dexter's Laboratory episode "Chicken Scratch". When Bubbles and Blossom suffered from swine flu and turned into warthogs, the same thing when Dexter also suffered from chicken pox and he turned into a literal chicken.
  • The Powerpuff Clock design resembles the Powerpuff Hotline.
  • Running Gag: The Schedulebot shouting "Antidote time!".
  • The common symptoms of a spotted piglet fever were:
    • Snorting.
    • Sneezing.
    • Red spots.
    • Imagining climbing Mt. Everest.
  • The scene after Buttercup gets Blossom and Bubbles home where it shows the girls home is a music piece recycled from the 1999 Fox series, Family Guy.
  • When Blossom is in bed, she's wearing her nightgown. When she's writing fractions on her paper, she's seen in her regular outfit.
  • Possible Error: When Buttercup is screaming at the Schedulebot, her lips only move for two frames and are very off sync. This was likely intentional to make it look something scary.
  • This is the second time Buttercup burped when she was a drinking soda.
  • This is the third episode without the outro when the day is saved.
  • This episode marks Schedulebot's first appearance in the series as a whole.
  • Buttercup mentioned about going to school like a nerd and it happened later in "Buttercup vs. Math".
ve Episodes
Season 1
Escape from Monster IslandPrincess ButtercupThe StayoverPainbowHorn, Sweet HornMan UpBye Bye, BellumLittle Octi LostStrong-ArmedPower-Up PuffTiara TroubleThe Wrinklegruff GalsArachno-RomancePuffdora's BoxBlue Ribbon BluesFrenemyOnce Upon a TownsvilleMan Up 2: Still Man-ingViral SpiralBubbles of the OperaSister SitterOdd Bubbles OutPresidential PunchoutCheep ThrillsFashion ForwardIn the Garden of Good and EddieRoad Trippin'The Big SleepThe Secret Life of Blossom PowerpuffHalt and Catch SilicoSecret Swapper of DoomRainy DayThe SquasheningElectric ButtercupProfessor ProofedPoorbucksSnow MonthSomewhere Over the SwingsetPeople Pleaser
Season 2
The Last DonnycornGreen Wing15 Minutes of FameSplitsvilleClawdadSuper Sweet 6A Star Is BlossomMini Golf MadnessSummer BummerThe Tell Tale SchedulebotMusclecupTake Your Kids to Dooms DayThe Bubbles-Sitters ClubButtercup vs. MathHome, Sweet HomesickMemory Lane of PainSpider SenseImagine ThatPhantasm ChasmTooth or ConsequencesMonkey LoveBridezillaFind Your BlissBliss ReminisceBlisster SisterBlisster SisterBlisstersweet SymphonyMidnight at the Mayor's MansionYou're a Good Man, Mojo JojoThe Trouble With BubblesSugar, Spice, and Super LiceThe Buttercup JobA Slight HiccupToy PloyDerby DolliesBubbles the BlueDeb O’NairMan Up 3: The Good, the Bad, and the ManlyThe Blossom FilesNot So Secret Service
Season 3
Never Been BlissedAliverWorshipBlossom3Mojo the GreatTrouble ClefSave the DateCan't Buy LoveLargoBlundercupRagnarock and RollTotal Eclipse of the KartThe Long Skate HomeQuarantineIn the DoghouseSalamanderSmall World: Abra-DisasterSmall World: Stone Cold SpiderSmall World: Maze DazeSmall World: Heart to HeartstoneWitch's CrewThe GiftOh, Daisy!Brain FreezeLights Out!Bucketboy!The FogThe SpoonCat BurglarHustlecupRebel RebelOur Brand is ChaosTagalongBrainLordCheckin Out!Drama BombWatch It!Man Up 4: The Donnyest GameThe Oct-FatherSideline Dad
Who's Got the Power?Air ButtercupBubbles' Beauty Blog (but on Video)Run, Blossom, Run!Ping Pong ZBubbs & Donny Get the MailBedtimeMojo Builds a ShelfI’ll Be BakeBlissfully Unaware