Farmsville is a town located in Pokey Oaks County. In Beat Your Greens, the Narrator states that it is an agricultural community, known for harvesting vegetables such as broccolli. Farmsville is shown to ship produce to markets in nearby areas, including Malph's in Townsville.
When the Broccoloids reach Earth, they infest Farmsville's broccolli with "receptor spores" by launching a "Sporepedo" into a Farmsville field. After the broccoli is shipped to Townsville, it is consumed by Townsville's adult citizens, who fall under the Broccolloids' mind control. The Powerpuff Girls fly to Farmsville to investigate. When the Broccoloids began invading Earth directly, the Girls enlisted the other children (who refused to eat their broccolli earlier) to help fight the Broccoloids.