Citiesville is a city not too far from Townsville, located in Pokey Oaks County. It is an industrial city with high rise buildings built in the first half of the 20th century. The city is mainly a commuter city, connected to Townsville via a historic suspension bridge.
Crime in Citiesville is rampant, and the police are largely unable to prevent criminal activity. However, Citiesville's government banned superheroes and the use of superpowers altogether after the Powerpuff Girls destroyed the town's historic bridge while trying to catch some crooks.
Unlike Townsville, in Citiesville, the mayor is a competent and very busy individual. There are no modern skyscrapers and the buildings are not brightly colored and cheerful. The citizens are cruel even if they aren't villains, and students are not allowed to just leave in the middle of class. Also, the destruction of irreplaceable city landmarks to catch petty criminals is not tolerated.
The town of Citiesville only appeared in "Town and Out." It was meant to be a more "realistic" city, as opposed to Townsville, and was meant to act as a deconstruction of how the Powerpuff Girls' brand of heroics would affect real life.
Seventeen years later, the town of Citiesville was mentioned in name only in the 2016 series episode "The Last Donnycorn", although it is not shown at all in that episode.
- The design of Citiesville City Hall is based on Los Angeles City Hall in Los Angeles, CA.
- The design of the Citiesville Bridge is based on the Brooklyn Bridge in New York, NY.